Sildenafil (Oral Route) Side Effects – Mayo Clinic

2.4 Dosage Adjustments Due to Drug Interactions. Ritonavir. The recommended dose for ritonavir-treated patients is 25 mg prior to sexual activity and the recommended maximum dose is 25mg within a 48hour period because concomitant administration increased the blood levels of sildenafil by 11-fold [see Warnings and Precautions (5.6), Drug Interactions (7.4), and Clinical Pharmacology (12.3)]. Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It is also sometimes used off-label for the treatment of Maximum plasma concentrations of sildenafil dosed at the Food and Drug Administration (FDA) approved schedule of 20 mg 3 times daily are achieved 1 hour after half life sildenafil The terminal half-life of sildenafil is 3тАУ5 h; therefore, the drug’s therapeutic response is expected to be sustained for at least 3 h following a dose of 100 mg. Sildenafil is a phosphodiesterase inhibitor used for erectile dysfunction and pulmonary arterial hypertension. Its half-life is 4 to 5 hours and it is metabolized by CYP3A4 and CYP2C9. After 4 hours, half of the Viagra has been broken down by the liver. It continues to decrease over the next 20 hours. Viagra may take longer to work if you take it after a fatty meal because fat slows down absorption in your stomach.

This sildenafil half life calculator shows how sildenafil accumulates and how long it stays in your body. Get dose and frequency with ease!

Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily. 2.4 Dosage Adjustments Due to Drug Interactions. Ritonavir. The recommended dose for ritonavir-treated patients is 25 mg prior to sexual activity and the recommended maximum dose is 25mg within a 48hour period because concomitant administration increased the blood levels of sildenafil by 11-fold [see Warnings and Precautions (5.6), Drug Interactions (7.4), and Clinical Pharmacology (12.3)]. sildenafil at walmart Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud’s phenomenon. [9] Sildenafil under the name Viagra is used to treat erectile dysfunction (impotence) in men. Another brand of sildenafil is Revatio, which is used to treat pulmonary arterial